Located in North Eastern Tanzania, Mkomazi National Park is bordered by Tsavo West National Park in Kenya to the north-east and by the Pare Mountains to the south-west. The park lies at the southern edge of the great arc of the Sahel region, between the Sahara to the north and a more humid zone (Sudan) to the south. The 3,701 km2 Mkomazi Park is predominantly dry and vegetated mostly by savanna vegetation.
The nature is dry open savanna dominated by acacia-commiphora vegetation, which is an ideal habitat for elephant, African buffalo, lion, leopard, lesser kudu, fringe-eared oryx, aardwolf, and gerenuk. In addition, the park is a refuge for two highly endangered species, the captivating black rhino and the African wild dog, both of which were successfully reintroduced in the 1990s.
Just over 390 species of birds have been recorded in Mkomazi, making it an ideal destination for birdwatchers. It was recently in 2007 that Mkomazi was upgraded to a national park.